BDBM50152703 3-((R)-2-Amino-2-phenyl-ethyl)-5-[2-(4-chloro-phenyl)-thiazol-4-yl]-1-(2,6-difluoro-benzyl)-6-methyl-1H-pyrimidine-2,4-dione::CHEMBL183938

SMILES Cc1c(-c2csc(n2)-c2ccc(Cl)cc2)c(=O)n(C[C@H](N)c2ccccc2)c(=O)n1Cc1c(F)cccc1F

InChI Key InChIKey=SEPWPJVHMOIGQX-UHFFFAOYSA-N

Data  1 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50152703   

TargetGonadotropin-releasing hormone receptor(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50152703(3-((R)-2-Amino-2-phenyl-ethyl)-5-[2-(4-chloro-phen...)
Affinity DataKi:  15nMAssay Description:Binding affinity towards cloned human Gonadotropin-releasing hormone receptor expressed in RBL cells was determined by using [125I]GnRH as radioligan...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed