BDBM50152553 4-[5-(4-Chloro-3-fluoro-phenyl)-thiophen-2-yl]-2,4-dioxo-butyric acid::CHEMBL361960

SMILES OC(=O)C(=O)CC(=O)c1ccc(s1)-c1ccc(Cl)c(F)c1

InChI Key InChIKey=COJHFTCPXJOAGP-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50152553   

TargetFlap endonuclease 1(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM50152553(4-[5-(4-Chloro-3-fluoro-phenyl)-thiophen-2-yl]-2,4...)
Affinity DataIC50: 570nMAssay Description:Concentration required for 50% inhibition of Flap endonuclease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetDNA excision repair protein ERCC-5(Human)
Athersys

Curated by ChEMBL
LigandPNGBDBM50152553(4-[5-(4-Chloro-3-fluoro-phenyl)-thiophen-2-yl]-2,4...)
Affinity DataIC50: 900nMAssay Description:Concentration required for 50% inhibition of Xeroderma pigmentosum GMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed