BDBM50152532 2,2-dimethyl-3-phenylpropyl(S)-1,2-dioxo-1-((R)-1-phenylethylamino)heptan-3-ylcarbamate::CHEMBL182775::[(S)-1-((R)-1-Phenyl-ethylaminooxalyl)-pentyl]-carbamic acid 2,2-dimethyl-3-phenyl-propyl ester

SMILES CCCC[C@H](NC(=O)OCC(C)(C)Cc1ccccc1)C(=O)C(=O)N[C@H](C)c1ccccc1

InChI Key InChIKey=NMXQSPUYSZKXOQ-UHFFFAOYSA-N

Data  6 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50152532   

TargetPro-cathepsin H(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50152532([(S)-1-((R)-1-Phenyl-ethylaminooxalyl)-pentyl]-car...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of 50 uM L-Arg-beta-naphthalamide binding to human cathepsin H in fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin B(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50152532([(S)-1-((R)-1-Phenyl-ethylaminooxalyl)-pentyl]-car...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibition of 10 uM Cbz-Phe-Arg-AMC binding to human cathepsin B in fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin S(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50152532([(S)-1-((R)-1-Phenyl-ethylaminooxalyl)-pentyl]-car...)
Affinity DataIC50: 20nMAssay Description:Inhibition of 10 uM Cbz-Val-Val-Arg-AMC binding to human cathepsin S in fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50152532([(S)-1-((R)-1-Phenyl-ethylaminooxalyl)-pentyl]-car...)
Affinity DataIC50: 13nMAssay Description:Inhibition of human cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProcathepsin L(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50152532([(S)-1-((R)-1-Phenyl-ethylaminooxalyl)-pentyl]-car...)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of 5 uM Cbz-Phe-Arg-AMC human cathepsin L in fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCathepsin K(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50152532([(S)-1-((R)-1-Phenyl-ethylaminooxalyl)-pentyl]-car...)
Affinity DataIC50: 12.9nMAssay Description:Inhibition of human cathepsin KMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed