BDBM50152517 CHEMBL359564::{1-[4-(Chroman-3-ylmethoxy)-benzoyl]-2-methyl-1H-indol-4-yl}-acetic acid

SMILES Cc1cc2c(CC(O)=O)cccc2n1C(=O)c1ccc(OCC2COc3ccccc3C2)cc1

InChI Key InChIKey=YSSBWOZPOQDJSI-UHFFFAOYSA-N

Data  6 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 6 hits for monomerid = 50152517   

TargetProstaglandin D2 receptor(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50152517({1-[4-(Chroman-3-ylmethoxy)-benzoyl]-2-methyl-1H-i...)
Affinity DataKi:  180nMAssay Description:Ability to inhibit the binding of [3H]PGD-2 radioligand to membranes of CHO cells stably expressing mouse Prostaglandin D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP2 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50152517({1-[4-(Chroman-3-ylmethoxy)-benzoyl]-2-methyl-1H-i...)
Affinity DataKi:  280nMAssay Description:Ability to inhibit the binding of [3H]-PGD-2 radioligand to membranes of CHO cells stably expressing mouse Prostaglandin E receptor EP2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin D2 receptor(Human)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50152517({1-[4-(Chroman-3-ylmethoxy)-benzoyl]-2-methyl-1H-i...)
Affinity DataKi:  390nMAssay Description:Ability to inhibit the binding of [3H]PGD-2 radioligand to membranes of CHO cells stably expressing human Prostaglandin D2 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP4 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50152517({1-[4-(Chroman-3-ylmethoxy)-benzoyl]-2-methyl-1H-i...)
Affinity DataKi:  3.50E+3nMAssay Description:Ability to inhibit the binding of [3H]PGD-2 radioligand to membranes of CHO cells stably expressing mouse Prostaglandin E receptor EP4More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP3 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50152517({1-[4-(Chroman-3-ylmethoxy)-benzoyl]-2-methyl-1H-i...)
Affinity DataKi: >1.00E+4nMAssay Description:Ability to inhibit the binding of [3H]PGD-2 radioligand to membranes of CHO cells stably expressing mouse Prostaglandin E receptor EP3More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProstaglandin E2 receptor EP1 subtype(Mouse)
Minase Research Institute

Curated by ChEMBL
LigandPNGBDBM50152517({1-[4-(Chroman-3-ylmethoxy)-benzoyl]-2-methyl-1H-i...)
Affinity DataKi: >1.00E+4nMAssay Description:Ability to inhibit the binding of [3H]PGD-2 radioligand to membranes of CHO cells stably expressing mouse Prostaglandin E receptor EP1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed