BDBM50152029 CHEMBL3775899

SMILES Clc1ccc(CC2CCN(CCc3cnn(c3)-c3nccc4c3nc[nH]c4=O)CC2)cc1

InChI Key InChIKey=MIHKHZZRKYZHJU-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50152029   

TargetLysine-specific demethylase 3A(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50152029(CHEMBL3775899)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of KDM3A (unknown origin) using biotin-H3K9me2 (1 to 21 residues) as substrate preincubated for 15 mins followed by substrate addition mea...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details Article
PubMed
TargetLysine-specific demethylase 5B(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50152029(CHEMBL3775899)
Affinity DataIC50: 14nMAssay Description:Inhibition of KDM5B (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details Article
PubMed
TargetLysine-specific demethylase 4A(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50152029(CHEMBL3775899)
Affinity DataIC50: 126nMAssay Description:Inhibition of human N-terminal His-tagged KDM4A (1 to 359 residues) expressed in Escherichia coli using biotin-H3K9me3 as substrate preincubated for ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details Article
PubMed
TargetLysine-specific demethylase 4B(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50152029(CHEMBL3775899)
Affinity DataIC50: 50nMAssay Description:Inhibition of recombinant human N-terminal GST-tagged KDM4B (1 to 500 residues) expressed in baculovirus infected sf9 cells using biotin-H3K9me3 as s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details Article
PubMed
TargetLysine-specific demethylase 5C(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50152029(CHEMBL3775899)
Affinity DataIC50: 23nMAssay Description:Inhibition of KDM5C (unknown origin) using biotin-H3K4me3 as substrate preincubated for 15 mins followed by substrate addition measured after 20 mins...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details Article
PubMed
TargetLysine-specific demethylase 6B(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50152029(CHEMBL3775899)
Affinity DataIC50: 4.85E+4nMAssay Description:Inhibition of KDM6B (unknown origin) using biotin-H3K27me3 (21 to 44 residues) as substrate preincubated for 15 mins followed by substrate addition m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details Article
PubMed
TargetLysine-specific demethylase 2A(Human)
The Institute of Cancer Research

Curated by ChEMBL
LigandPNGBDBM50152029(CHEMBL3775899)
Affinity DataIC50: 8.60E+3nMAssay Description:Inhibition of KDM2A (unknown origin) using biotin-H3K36me2 (28 to 48 residues) as substrate preincubated for 15 mins followed by substrate addition m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/26/2017
Entry Details Article
PubMed