BDBM50151859 CHEMBL3775876

SMILES C/C(C)=C\CC/C(C)=C/CCn1cc(CC(P(=O)([O-])[O-])P(=O)([O-])[O-])nn1

InChI Key InChIKey=GADOQTNZNVQUEX-UHFFFAOYSA-J

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50151859   

TargetFarnesyl pyrophosphate synthase(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50151859(CHEMBL3775876)
Affinity DataIC50: 2.80E+4nMAssay Description:Inhibition of recombinant FDPS (unknown origin) assessed as radiolabeled FPP formation preincubated for 10 mins followed by addition of 10 uM GPP sub...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2017
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50151859(CHEMBL3775876)
Affinity DataIC50: 45nMAssay Description:Inhibition of recombinant GGDPS (unknown origin) assessed as radiolabeled GGPP formation preincubated for 10 mins followed by addition of 10 uM FPP s...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2017
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50151859(CHEMBL3775876)
Affinity DataIC50: 170nMAssay Description:Inhibition of recombinant GGDPS (unknown origin) using FPP as substrate pretreated for 10 mins followed by substrate addition after 30 mins in presen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/26/2019
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50151859(CHEMBL3775876)
Affinity DataIC50: 170nMAssay Description:Inhibition of recombinant GGDPS (unknown origin) using FPP as substrate pretreated for 10 mins followed by substrate addition measured after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed
TargetGeranylgeranyl pyrophosphate synthase(Human)
University of Iowa

Curated by ChEMBL
LigandPNGBDBM50151859(CHEMBL3775876)
Affinity DataIC50: 170nMAssay Description:Inhibition of recombinant GGDPS (unknown origin) using FPP as substrate pretreated for 10 mins followed by substrate addition measured after 30 mins ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/15/2020
Entry Details Article
PubMed