BDBM50151848 CHEMBL3774827

SMILES CN(C)C(=O)N1CCC(CC1)Oc1nc(nc(n1)-c1cccc2[nH]ncc12)N1CCOCC1

InChI Key InChIKey=IYYBADRIAWFQRA-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50151848   

LigandPNGBDBM50151848(CHEMBL3774827)
Affinity DataIC50: 60nMAssay Description:Inhibition of human recombinant PI3K-alpha using phosphatidylinositol biphosphate as substrate preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2017
Entry Details Article
PubMed
TargetCytochrome P450 3A4(Human)
Sphaera Pharma

Curated by ChEMBL
LigandPNGBDBM50151848(CHEMBL3774827)
Affinity DataIC50: 1.50E+4nMAssay Description:Inhibition of CYP3A4 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2017
Entry Details Article
PubMed
TargetCytochrome P450 2C19(Human)
Sphaera Pharma

Curated by ChEMBL
LigandPNGBDBM50151848(CHEMBL3774827)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2C19 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2017
Entry Details Article
PubMed
TargetCytochrome P450 2D6(Human)
Sphaera Pharma

Curated by ChEMBL
LigandPNGBDBM50151848(CHEMBL3774827)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of CYP2D6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2017
Entry Details Article
PubMed
LigandPNGBDBM50151848(CHEMBL3774827)
Affinity DataIC50: 60nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/12/2025
Entry Details
PubMed