BDBM50151710 CHEMBL3775745

SMILES CNC(=O)CNc1nc(nc(n1)-c1cccc(O)c1)N1CCOCC1

InChI Key InChIKey=NQVYUSFEPDRSPV-UHFFFAOYSA-N

Data  2 IC50

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50151710   

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Sphaera Pharma

Curated by ChEMBL

LigandBDBM50151710(CHEMBL3775745)Copy SMILESCopy InChI

Affinity DataIC50: 730nMAssay Description:Inhibition of human recombinant PI3K-alpha using phosphatidylinositol biphosphate as substrate preincubated for 15 mins followed by substrate additio...More data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
7/1/2017
Entry Details Article
Copy Entry DOIPubMed
Copy Rxn URL

TargetPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform(Human)
Sphaera Pharma

Curated by ChEMBL

LigandBDBM50151710(CHEMBL3775745)Copy SMILESCopy InChI

Affinity DataIC50: 730nMMore data for this Ligand-Target Pair

Target InfoPDBKEGG
UniProtKB/SwissProt
GoogleScholar

Ligand InfoCHEMBLPC cidPC sidSimilars

In Depth
Date in BDB:
10/12/2025
Entry Details
Copy Entry DOIPubMed
Copy Rxn URL