BDBM50151645 8''-chloro-5''-[2-(1,4-oxazinan-4-yl)ethoxy]spiro[cyclohexane-1,4''-(1'',2'',3'',4''-tetrahydroquinazoline)]-2''-one::CHEMBL185523

SMILES Clc1ccc(OCCN2CCOCC2)c2c1NC(=O)NC21CCCCC1

InChI Key InChIKey=NDIGGVVRAHQVPZ-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50151645   

LigandPNGBDBM50151645(8''-chloro-5''-[2-(1,4-oxazinan-4-yl)ethoxy]spiro[...)
Affinity DataIC50: 2.90E+4nMAssay Description:Inhibition of human PDE1 partially purified from THP-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50151645(8''-chloro-5''-[2-(1,4-oxazinan-4-yl)ethoxy]spiro[...)
Affinity DataIC50: 1.01E+5nMAssay Description:Inhibition of human PDE5 partially purified from MCF-7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50151645(8''-chloro-5''-[2-(1,4-oxazinan-4-yl)ethoxy]spiro[...)
Affinity DataIC50: 1.01E+5nMAssay Description:Inhibition of human PDE3A3 expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50151645(8''-chloro-5''-[2-(1,4-oxazinan-4-yl)ethoxy]spiro[...)
Affinity DataIC50: 7.35E+3nMAssay Description:Inhibition of human PDE4D3 expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50151645(8''-chloro-5''-[2-(1,4-oxazinan-4-yl)ethoxy]spiro[...)
Affinity DataIC50: 30nMAssay Description:Inhibition of human PDE7A1 expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed