BDBM50151642 8''-chloro-5''-(2-methylaminoethoxy)spiro[cyclohexane-1,4''-(1'',2'',3'',4''-tetrahydroquinazoline)]-2''-one::CHEMBL184979

SMILES CNCCOc1ccc(Cl)c2NC(=O)NC3(CCCCC3)c12

InChI Key InChIKey=UQZKFTSBRMZGHX-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50151642   

LigandPNGBDBM50151642(8''-chloro-5''-(2-methylaminoethoxy)spiro[cyclohex...)
Affinity DataIC50: 1.01E+5nMAssay Description:Inhibition of human PDE5 partially purified from MCF-7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50151642(8''-chloro-5''-(2-methylaminoethoxy)spiro[cyclohex...)
Affinity DataIC50: 7.24E+4nMAssay Description:Inhibition of human PDE1 partially purified from THP-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50151642(8''-chloro-5''-(2-methylaminoethoxy)spiro[cyclohex...)
Affinity DataIC50: 1.01E+5nMAssay Description:Inhibition of human PDE3A3 expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50151642(8''-chloro-5''-(2-methylaminoethoxy)spiro[cyclohex...)
Affinity DataIC50: 5.32E+4nMAssay Description:Inhibition of human PDE4D3 expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50151642(8''-chloro-5''-(2-methylaminoethoxy)spiro[cyclohex...)
Affinity DataIC50: 960nMAssay Description:Inhibition of human PDE7A1 expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed