BDBM50151634 5-[8''-chloro-2''-oxospiro[cyclohexane-1,4''-(1'',2'',3'',4''-tetrahydroquinazoline)]-5-yloxymethyl]-2-furoic acid::CHEMBL365447

SMILES OC(=O)c1ccc(COc2ccc(Cl)c3NC(=O)NC4(CCCCC4)c23)o1

InChI Key InChIKey=VLZBPFMKLZZNRU-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50151634   

LigandPNGBDBM50151634(5-[8''-chloro-2''-oxospiro[cyclohexane-1,4''-(1'',...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of human PDE1 partially purified from THP-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50151634(5-[8''-chloro-2''-oxospiro[cyclohexane-1,4''-(1'',...)
Affinity DataIC50: 1.01E+5nMAssay Description:Inhibition of human PDE5 partially purified from MCF-7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50151634(5-[8''-chloro-2''-oxospiro[cyclohexane-1,4''-(1'',...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human PDE7A1 expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50151634(5-[8''-chloro-2''-oxospiro[cyclohexane-1,4''-(1'',...)
Affinity DataIC50: 1.13E+3nMAssay Description:Inhibition of human PDE4D3 expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50151634(5-[8''-chloro-2''-oxospiro[cyclohexane-1,4''-(1'',...)
Affinity DataIC50: 1.08E+4nMAssay Description:Inhibition of human PDE3A3 expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed