BDBM50151597 3-[8''-chloro-2''-oxospiro[cyclohexane-1,4''-(1'',2'',3'',4''-tetrahydroquinazoline)]-6-yl]benzoic acid::CHEMBL427505

SMILES OC(=O)c1cccc(c1)-c1cc(Cl)c2NC(=O)NC3(CCCCC3)c2c1

InChI Key InChIKey=FXUFWAVOAYRFKB-UHFFFAOYSA-N

Data  5 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50151597   

LigandPNGBDBM50151597(3-[8''-chloro-2''-oxospiro[cyclohexane-1,4''-(1'',...)
Affinity DataIC50: 1.26E+4nMAssay Description:In vitro inhibition of human Phosphodiesterase 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50151597(3-[8''-chloro-2''-oxospiro[cyclohexane-1,4''-(1'',...)
Affinity DataIC50: 710nMAssay Description:In vitro inhibition of human Phosphodiesterase 1 partially purified from THP-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50151597(3-[8''-chloro-2''-oxospiro[cyclohexane-1,4''-(1'',...)
Affinity DataIC50: 740nMAssay Description:In vitro inhibition of human Phosphodiesterase 4D3 expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50151597(3-[8''-chloro-2''-oxospiro[cyclohexane-1,4''-(1'',...)
Affinity DataIC50: 1.67E+4nMAssay Description:In vitro inhibition of human Phosphodiesterase 3A3 expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50151597(3-[8''-chloro-2''-oxospiro[cyclohexane-1,4''-(1'',...)
Affinity DataIC50: 20nMAssay Description:In vitro inhibition of human Phosphodiesterase 7A1 expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed