BDBM50151593 8''-chloro-6''-phenylspiro[cyclohexane-1,4''-(1'',2'',3'',4''-tetrahydroquinazoline)]-2''-one::CHEMBL182703

SMILES Clc1cc(cc2c1NC(=O)NC21CCCCC1)-c1ccccc1

InChI Key InChIKey=OFWGHMAISKOSQV-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50151593   

LigandPNGBDBM50151593(8''-chloro-6''-phenylspiro[cyclohexane-1,4''-(1'',...)
Affinity DataIC50: 3.26E+3nMAssay Description:Inhibition of human Phosphodiesterase 1 partially purified from THP-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50151593(8''-chloro-6''-phenylspiro[cyclohexane-1,4''-(1'',...)
Affinity DataIC50: 6.98E+4nMAssay Description:Inhibition of human Phosphodiesterase 5More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50151593(8''-chloro-6''-phenylspiro[cyclohexane-1,4''-(1'',...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human Phosphodiesterase 7A1 expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50151593(8''-chloro-6''-phenylspiro[cyclohexane-1,4''-(1'',...)
Affinity DataIC50: 1.01E+5nMAssay Description:Inhibition of human Phosphodiesterase 3A3 expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50151593(8''-chloro-6''-phenylspiro[cyclohexane-1,4''-(1'',...)
Affinity DataIC50: 1.42E+3nMAssay Description:Inhibition of human Phosphodiesterase 4D3 expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50151593(8''-chloro-6''-phenylspiro[cyclohexane-1,4''-(1'',...)
Affinity DataIC50: 16nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
TargetPlatelet-derived growth factor receptor alpha/beta(Mouse)
Southern Medical University

Curated by ChEMBL
LigandPNGBDBM50151593(8''-chloro-6''-phenylspiro[cyclohexane-1,4''-(1'',...)
Affinity DataIC50: 1.42E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed