BDBM50151547 5-[5-(4-Chloro-phenyl)-3-methyl-3H-[1,3,4]thiadiazol-(2Z)-ylideneamino]-2-fluoro-benzoic acid::CHEMBL182574

SMILES Cn1nc(s\c1=N/c1ccc(F)c(c1)C(O)=O)-c1ccc(Cl)cc1

InChI Key InChIKey=RTVAXMAAIDVFHH-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50151547   

LigandPNGBDBM50151547(5-[5-(4-Chloro-phenyl)-3-methyl-3H-[1,3,4]thiadiaz...)
Affinity DataIC50: 1.79E+4nMAssay Description:Inhibition of human Phosphodiesterase 5 purified from MCF-7 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50151547(5-[5-(4-Chloro-phenyl)-3-methyl-3H-[1,3,4]thiadiaz...)
Affinity DataIC50: 2.16E+4nMAssay Description:Inhibition of human Phosphodiesterase 1 purified from THP-1 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50151547(5-[5-(4-Chloro-phenyl)-3-methyl-3H-[1,3,4]thiadiaz...)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of human Phosphodiesterase 3A3 expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50151547(5-[5-(4-Chloro-phenyl)-3-methyl-3H-[1,3,4]thiadiaz...)
Affinity DataIC50: 160nMAssay Description:Inhibition of human Phosphodiesterase 7A1 expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50151547(5-[5-(4-Chloro-phenyl)-3-methyl-3H-[1,3,4]thiadiaz...)
Affinity DataIC50: 3.97E+4nMAssay Description:Inhibition of human Phosphodiesterase 4D3 expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50151547(5-[5-(4-Chloro-phenyl)-3-methyl-3H-[1,3,4]thiadiaz...)
Affinity DataIC50: 160nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed
LigandPNGBDBM50151547(5-[5-(4-Chloro-phenyl)-3-methyl-3H-[1,3,4]thiadiaz...)
Affinity DataIC50: 3.97E+3nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2025
Entry Details
PubMed