BDBM50151526 CHEMBL363097::N-(4-{5-[(Z)-Cyclohexylimino]-4-methyl-4,5-dihydro-[1,3,4]thiadiazol-2-yl}-phenyl)-acetamide::US8637528, OM956

SMILES CC(=O)Nc1ccc(cc1)-c1nn(C)\c(=N\C2CCCCC2)s1

InChI Key InChIKey=HMLIQWYFUWNFED-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50151526   

LigandPNGBDBM50151526(CHEMBL363097 | US8637528, OM956 | N-(4-{5-[(Z)-Cyc...)
Affinity DataIC50: 140nMpH: 8.0Assay Description:The assay method used was a scintillation proximity assay (SPA) (obtained from GE Healthcare, Product Code TRKQ7100), with [3H]-cGMP as the substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
Go to US Patent

LigandPNGBDBM50151526(CHEMBL363097 | US8637528, OM956 | N-(4-{5-[(Z)-Cyc...)
Affinity DataIC50: 144nMpH: 8.0Assay Description:The assay method used was a scintillation proximity assay (SPA) (obtained from GE Healthcare, Product Code TRKQ7100), with [3H]-cGMP as the substrate...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/22/2014
Entry Details
Go to US Patent

LigandPNGBDBM50151526(CHEMBL363097 | US8637528, OM956 | N-(4-{5-[(Z)-Cyc...)
Affinity DataIC50: 3.43E+4nMAssay Description:Inhibition of human Phosphodiesterase 4D3 expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50151526(CHEMBL363097 | US8637528, OM956 | N-(4-{5-[(Z)-Cyc...)
Affinity DataIC50: 60nMAssay Description:Inhibition of human Phosphodiesterase 7A1 expressed in baculovirus infected Sf9 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed