BDBM50151521 4-(3-Chloro-phenyl)-5-[(4-cyano-phenyl)-(3-methyl-3H-imidazol-4-yl)-methoxymethyl]-1-methyl-6-oxo-1,6-dihydro-pyridine-2-carbonitrile::CHEMBL185492

SMILES Cn1cncc1C(OCc1c(cc(C#N)n(C)c1=O)-c1cccc(Cl)c1)c1ccc(cc1)C#N

InChI Key InChIKey=MVEQWLJJQYFYPG-UHFFFAOYSA-N

Data  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50151521   

LigandPNGBDBM50151521(4-(3-Chloro-phenyl)-5-[(4-cyano-phenyl)-(3-methyl-...)
Affinity DataIC50: 1.00E+4nMAssay Description:inhibitory concentration needed to to reduce the bovine GGTase-catalyzed incorporation of [3H]-FPP into a biotin-linked K-ras (B) decapeptideMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50151521(4-(3-Chloro-phenyl)-5-[(4-cyano-phenyl)-(3-methyl-...)
Affinity DataEC50:  11nMAssay Description:Reduced farnesylation of H-ras transformed NIH3T3 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed