BDBM50151375 CHEMBL3774414

SMILES COc1ccc(cc1OCCCC(=O)NO)N(C)c1nc(C)nc2ccccc12

InChI Key InChIKey=FWXZZFONXWYSEF-UHFFFAOYSA-N

Data  12 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 13 hits for monomerid = 50151375   

TargetHistone deacetylase 1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50151375(CHEMBL3774414)
Affinity DataIC50: 422nMAssay Description:Inhibition of human recombinant HDAC1 using AMC labeled AC-peptide as substrate incubated for 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2017
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50151375(CHEMBL3774414)
Affinity DataIC50: 17nMAssay Description:Inhibition of human recombinant HDAC6 using AMC labeled AC-peptide as substrate incubated for 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2017
Entry Details Article
PubMed
TargetHistone deacetylase 8(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50151375(CHEMBL3774414)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of human recombinant HDAC8 using AMC labeled AC-peptide as substrate incubated for 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2017
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50151375(CHEMBL3774414)
Affinity DataEC50:  59nMAssay Description:Inhibition of HDAC6 in human HeLa cells assessed as induction of tubulin acetylation incubated for 6 hrs by cytoblot assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2017
Entry Details Article
PubMed
TargetHistone deacetylase 4(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50151375(CHEMBL3774414)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant HDAC4 (unknown origin) using AMC labeled AC-peptide as substrate incubated for 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2017
Entry Details Article
PubMed
TargetHistone deacetylase 2(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50151375(CHEMBL3774414)
Affinity DataIC50: 386nMAssay Description:Inhibition of recombinant HDAC2 (unknown origin) using AMC labeled AC-peptide as substrate incubated for 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2017
Entry Details Article
PubMed
TargetHistone deacetylase 3(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50151375(CHEMBL3774414)
Affinity DataIC50: 439nMAssay Description:Inhibition of recombinant HDAC3 (unknown origin) using AMC labeled AC-peptide as substrate incubated for 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2017
Entry Details Article
PubMed
TargetHistone deacetylase 5(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50151375(CHEMBL3774414)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant HDAC5 (unknown origin) using AMC labeled AC-peptide as substrate incubated for 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2017
Entry Details Article
PubMed
TargetHistone deacetylase 7(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50151375(CHEMBL3774414)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant HDAC7 (unknown origin) using AMC labeled AC-peptide as substrate incubated for 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2017
Entry Details Article
PubMed
TargetHistone deacetylase 9(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50151375(CHEMBL3774414)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant HDAC9 (unknown origin) using AMC labeled AC-peptide as substrate incubated for 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2017
Entry Details Article
PubMed
TargetPolyamine deacetylase HDAC10(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50151375(CHEMBL3774414)
Affinity DataIC50: 1.18E+3nMAssay Description:Inhibition of recombinant HDAC10 (unknown origin) using AMC labeled AC-peptide as substrate incubated for 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2017
Entry Details Article
PubMed
TargetHistone deacetylase 11(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50151375(CHEMBL3774414)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of recombinant HDAC11 (unknown origin) using AMC labeled AC-peptide as substrate incubated for 1 hr by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/1/2017
Entry Details Article
PubMed
TargetHistone deacetylase 6(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50151375(CHEMBL3774414)
Affinity DataIC50: 17nMAssay Description:Inhibition of HDAC6 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/19/2024
Entry Details
PubMed