BDBM50151365 5-(6-Ethoxy-[1,5]naphthyridin-2-yl)-4-pyridin-2-yl-thiazol-2-ylamine::CHEMBL360613

SMILES CCOc1ccc2nc(ccc2n1)-c1sc(N)nc1-c1ccccn1

InChI Key InChIKey=NKPNEZGIXTWKIJ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50151365   

TargetTGF-beta receptor type-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50151365(5-(6-Ethoxy-[1,5]naphthyridin-2-yl)-4-pyridin-2-yl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Stimulation of Transforming growth factor beta receptor I kinase in HepG2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50151365(5-(6-Ethoxy-[1,5]naphthyridin-2-yl)-4-pyridin-2-yl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity for Activin A receptor type II-like kinase (ALK5) in fluorescence polarization binding assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed