BDBM50151272 CHEMBL3769930

SMILES C(C1COC2(CCCCC2)O1)N1CCN(Cc2ccccc2)CC1

InChI Key InChIKey=SMEIMTHKRVPONN-UHFFFAOYSA-N

Data  5 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50151272   

TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50151272(CHEMBL3769930)
Affinity DataKi:  0.740nMAssay Description:Displacement of [3H](+)-pentazocine from sigma 1 receptor in guinea pig brain cortex membranes after 150 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetSigma non-opioid intracellular receptor 1(Human)
University of Pavia

Curated by ChEMBL
LigandPNGBDBM50151272(CHEMBL3769930)
Affinity DataKi:  0.740nMAssay Description:Binding affinity to sigma 1 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
TargetSigma non-opioid intracellular receptor 1(Guinea pig)
University of Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50151272(CHEMBL3769930)
Affinity DataKi:  0.741nMAssay Description:Displacement of [3H]-(+)-pentazocine from sigma-1 receptor in guinea pig brain membranes after 150 mins by liquid scintillation counting methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2017
Entry Details Article
PubMed
TargetSigma intracellular receptor 2(Human)
University of Pavia

Curated by ChEMBL
LigandPNGBDBM50151272(CHEMBL3769930)
Affinity DataKi:  35nMAssay Description:Binding affinity to sigma 2 receptor (unknown origin) assessed as inhibition constantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/15/2024
Entry Details
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Modena and Reggio Emilia

Curated by ChEMBL
LigandPNGBDBM50151272(CHEMBL3769930)
Affinity DataKi: <1.00E+3nMAssay Description:Displacement of [3H]8-OH-DPAT from human 5-HT1A expressed in human HeLa cells after 30 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/30/2017
Entry Details Article
PubMed