BDBM50151003 (S)-1-((S)-2-Amino-3,3-dimethyl-butyryl)-pyrrolidine-2-carbonitrile::CHEMBL1627303::CHEMBL363250::US11096924, DASH-inhibitors 9987::US11559537, Compound 9987

SMILES CC(C)(C)[C@H](N)C(=O)N1CCC[C@H]1C#N

InChI Key InChIKey=XGNBIYXILDDDQR-UHFFFAOYSA-N

Data  2 KI  15 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 17 hits for monomerid = 50151003   

TargetHomeobox protein PKNOX1(Human)
Tufts College

US Patent
LigandPNGBDBM50151003(CHEMBL1627303 | CHEMBL363250 | (S)-1-((S)-2-Amino-...)
Affinity DataIC50: 1.00E+8nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 8/9(Human)
Tufts College

US Patent
LigandPNGBDBM50151003(CHEMBL1627303 | CHEMBL363250 | (S)-1-((S)-2-Amino-...)
Affinity DataIC50: 120nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
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TargetProlyl endopeptidase(Human)
Tufts College

US Patent
LigandPNGBDBM50151003(CHEMBL1627303 | CHEMBL363250 | (S)-1-((S)-2-Amino-...)
Affinity DataIC50: 1.00E+5nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetProlyl endopeptidase FAP(Human)
Tufts College

US Patent
LigandPNGBDBM50151003(CHEMBL1627303 | CHEMBL363250 | (S)-1-((S)-2-Amino-...)
Affinity DataIC50: 700nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 2(Human)
Tufts College

US Patent
LigandPNGBDBM50151003(CHEMBL1627303 | CHEMBL363250 | (S)-1-((S)-2-Amino-...)
Affinity DataIC50: 1.00E+5nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 4(Human)
Tufts College

US Patent
LigandPNGBDBM50151003(CHEMBL1627303 | CHEMBL363250 | (S)-1-((S)-2-Amino-...)
Affinity DataIC50: 1.30nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 9(Human)
Tufts College

US Patent
LigandPNGBDBM50151003(CHEMBL1627303 | CHEMBL363250 | (S)-1-((S)-2-Amino-...)
Affinity DataIC50: 19nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 8(Human)
Tufts College

US Patent
LigandPNGBDBM50151003(CHEMBL1627303 | CHEMBL363250 | (S)-1-((S)-2-Amino-...)
Affinity DataIC50: 42nMAssay Description:This assay is described in Bachovchin et al. Nature Chemical Biology 10, 656-663 (2014). Briefly, purified enzymes are coupled to Luminex microsphere...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/19/2023
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 8/9(Human)
Tufts College

US Patent
LigandPNGBDBM50151003(CHEMBL1627303 | CHEMBL363250 | (S)-1-((S)-2-Amino-...)
Affinity DataIC50: 1.20E+5nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 4(Human)
Tufts College

US Patent
LigandPNGBDBM50151003(CHEMBL1627303 | CHEMBL363250 | (S)-1-((S)-2-Amino-...)
Affinity DataIC50: 7nMAssay Description:Inhibitory concentration against dipeptidylpeptidase IVMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProlyl endopeptidase FAP(Human)
Tufts College

US Patent
LigandPNGBDBM50151003(CHEMBL1627303 | CHEMBL363250 | (S)-1-((S)-2-Amino-...)
Affinity DataIC50: 7.00E+5nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 2(Human)
Tufts College

US Patent
LigandPNGBDBM50151003(CHEMBL1627303 | CHEMBL363250 | (S)-1-((S)-2-Amino-...)
Affinity DataIC50: 1.00E+8nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 4(Human)
Tufts College

US Patent
LigandPNGBDBM50151003(CHEMBL1627303 | CHEMBL363250 | (S)-1-((S)-2-Amino-...)
Affinity DataIC50: 1.30E+3nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 9(Human)
Tufts College

US Patent
LigandPNGBDBM50151003(CHEMBL1627303 | CHEMBL363250 | (S)-1-((S)-2-Amino-...)
Affinity DataIC50: 1.90E+4nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 8(Human)
Tufts College

US Patent
LigandPNGBDBM50151003(CHEMBL1627303 | CHEMBL363250 | (S)-1-((S)-2-Amino-...)
Affinity DataIC50: 4.20E+4nMAssay Description:EnzymesRecombinant human DPPIV (R&D Systems, Cat. No. 1180-SE)Recombinant human DPP8 (Enzo Life Sciences, Cat. No. BML-SE527)Recombinant human DPP9 (...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/6/2022
Entry Details
Go to US Patent

TargetDipeptidyl peptidase 4(Human)
Tufts College

US Patent
LigandPNGBDBM50151003(CHEMBL1627303 | CHEMBL363250 | (S)-1-((S)-2-Amino-...)
Affinity DataKi:  3.80nMAssay Description:In vitro test for inhibitory activity against human dipeptidyl peptidase IV.More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/26/2012
Entry Details Article

TargetDipeptidyl peptidase 4(Pig)
Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50151003(CHEMBL1627303 | CHEMBL363250 | (S)-1-((S)-2-Amino-...)
Affinity DataKi:  8nMAssay Description:In vitro inhibition of porcine Dipeptidylpeptidase IV.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed