BDBM50150793 2,2',6,6'-Tetrabromobisphenol A::2,2-Bis(3,5-dibromo-4-hydroxyphenyl)propane::3,3',5,5'-tetrabromobisphenol A::4,4'-(1-Methylethylidene)bis(2,6-dibromophenol)::4,4'-(2,2-propanediyl) bis[2,6-dibromo]phenol::4,4'-(propane-2,2-diyl)bis(2,6-dibromophenol)::4,4'-Isopropylidenebis(2,6-dibromophenol)::CHEMBL184450

SMILES CC(C)(c1cc(c(c(c1)Br)O)Br)c2cc(c(c(c2)Br)O)Br

InChI Key InChIKey=VEORPZCZECFIRK-UHFFFAOYSA-N

Data  3 IC50

PDB links: 4 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50150793   

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50150793(4,4'-(propane-2,2-diyl)bis(2,6-dibromophenol) | 3,...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibitory effect on human reticulocyte 15-lipoxygenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50150793(4,4'-(propane-2,2-diyl)bis(2,6-dibromophenol) | 3,...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibitory effect on human platelet 12-lipoxygenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Rabbit)
University of Chemistry and Technology Prague

Curated by ChEMBL
LigandPNGBDBM50150793(4,4'-(propane-2,2-diyl)bis(2,6-dibromophenol) | 3,...)
Affinity DataIC50: 500nMAssay Description:Inhibition of rabbit skeletal muscle microsomes SERCA1a by enzyme-coupled methodMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMed