BDBM50150789 2,6-dibromophenol::CHEMBL111507

SMILES c1cc(c(c(c1)Br)O)Br

InChI Key InChIKey=SSIZLKDLDKIHEV-UHFFFAOYSA-N

Data  1 KI  2 IC50  2 EC50

PDB links: 2 PDB IDs match this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 5 hits for monomerid = 50150789   

TargetPolyunsaturated fatty acid lipoxygenase ALOX15(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50150789(CHEMBL111507 | 2,6-dibromophenol)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory effect on human reticulocyte 15-lipoxygenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetPolyunsaturated fatty acid lipoxygenase ALOX12(Human)
University of California

Curated by ChEMBL
LigandPNGBDBM50150789(CHEMBL111507 | 2,6-dibromophenol)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibitory effect on human platelet 12-lipoxygenaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Human)
University of Chicago Medical Center

Curated by ChEMBL
LigandPNGBDBM50150789(CHEMBL111507 | 2,6-dibromophenol)
Affinity DataEC50:  1.00E+8nMAssay Description:Direct activation of human Gamma-aminobutyric acid A receptor alpha-1-beta-2-gamma-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-2/gamma-2(Human)
University of Chicago Medical Center

Curated by ChEMBL
LigandPNGBDBM50150789(CHEMBL111507 | 2,6-dibromophenol)
Affinity DataEC50:  1.00E+8nMAssay Description:Potentiation of GABA responses at human Gamma-aminobutyric acid A receptor alpha-1-beta-2-gamma-2More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
Target2,6-dichloro-p-hydroquinone 1,2-dioxygenase(Sphingobium chlorophenolicum)
Whitman College

LigandPNGBDBM50150789(CHEMBL111507 | 2,6-dibromophenol)
Affinity DataKi:  1.30E+4nMAssay Description:The rate of the enzymatic reaction was determined by measuring product formation by a spectrophotometric assay developed by Xun and co-worker with mo...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/5/2013
Entry Details Article
PubMed