BDBM50150771 5-(5,6-Dimethyl-pyrrolo[2,1-f][1,2,4]triazin-4-ylamino)-2-methyl-phenol::CHEMBL186001

SMILES Cc1cn2ncnc(Nc3ccc(C)c(O)c3)c2c1C

InChI Key InChIKey=NSSREJILCYZENK-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50150771   

TargetEpidermal growth factor receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50150771(5-(5,6-Dimethyl-pyrrolo[2,1-f][1,2,4]triazin-4-yla...)
Affinity DataIC50: 200nMAssay Description:In vitro inhibition of Epidermal growth factor receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50150771(5-(5,6-Dimethyl-pyrrolo[2,1-f][1,2,4]triazin-4-yla...)
Affinity DataIC50: 20nMAssay Description:In vitro inhibition of Vascular endothelial growth factor receptor 2More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetEpidermal growth factor receptor(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50150771(5-(5,6-Dimethyl-pyrrolo[2,1-f][1,2,4]triazin-4-yla...)
Affinity DataIC50: 23nMAssay Description:Inhibition of EGFR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed
TargetVascular endothelial growth factor receptor 2(Human)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50150771(5-(5,6-Dimethyl-pyrrolo[2,1-f][1,2,4]triazin-4-yla...)
Affinity DataIC50: 200nMAssay Description:Inhibition of VEGFR-2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/23/2024
Entry Details
PubMed