BDBM50150559 CHEMBL182361::{4-[5-(4-Fluoro-phenyl)-isoxazol-3-yl]-phenoxymethyl}-dimethyl-amine

SMILES CN(C)COc1ccc(cc1)-c1cc(on1)-c1ccc(F)cc1

InChI Key InChIKey=OCSBAOOQUDGZGV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50150559   

TargetC-X-C chemokine receptor type 1(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50150559({4-[5-(4-Fluoro-phenyl)-isoxazol-3-yl]-phenoxymeth...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of interleukin-8 induced elastase release from human neutrophilsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetC-X-C chemokine receptor type 1(Human)
Johnson and Johnson Pharmaceutical Research and Development

Curated by ChEMBL
LigandPNGBDBM50150559({4-[5-(4-Fluoro-phenyl)-isoxazol-3-yl]-phenoxymeth...)
Affinity DataIC50: 3.10E+3nMAssay Description:Inhibitory concentration against interleukin-8 receptor of human neutrophils by using [125I]IL-8 (0.125 nM) as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed