BDBM50150349 CHEMBL266407::Methanesulfonamide derivative

SMILES C[C@@H](CCC(O)=O)[C@@H]1CC[C@@H]2[C@H]3[C@@H](O)C[C@H]4C[C@@H](CC[C@@]4(C)[C@@H]3C[C@@H](O)[C@@]12C)OCCNC(=O)CCc1ccc(Oc2ccc(CN(Cc3ccccc3)c3cccc(NS(C)(=O)=O)c3C)cc2)cc1

InChI Key InChIKey=WJKLTGBFLMIJSC-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50150349   

TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150349(Methanesulfonamide derivative | CHEMBL266407)
Affinity DataIC50: 17nMAssay Description:Inhibition of [3H]dexamethasone binding to human glucocorticoid receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetGlucocorticoid receptor(Human)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150349(Methanesulfonamide derivative | CHEMBL266407)
Affinity DataIC50: 450nMAssay Description:Inhibition of glucocorticoid receptor Dexamethasone response in reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetSodium/bile acid cotransporter(Rat)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50150349(Methanesulfonamide derivative | CHEMBL266407)
Affinity DataIC50: 4nMAssay Description:Inhibition of [3H]taurocholate uptake in rat hepatocytesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed