BDBM50150252 1-Acetyl-4-(4-but-2-ynyloxy-benzenesulfonyl)-7-dimethylamino-2,3,4,5-tetrahydro-1H-benzo[e][1,4]diazepine-3-carboxylic acid hydroxyamide::CHEMBL184007

SMILES CC#CCOc1ccc(cc1)S(=O)(=O)N1Cc2cc(ccc2N(CC1C(=O)NO)C(C)=O)N(C)C

InChI Key InChIKey=BNLNSLPPTDOCGX-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50150252   

TargetCollagenase 3(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50150252(1-Acetyl-4-(4-but-2-ynyloxy-benzenesulfonyl)-7-dim...)
Affinity DataIC50: 17nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-13More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
LigandPNGBDBM50150252(1-Acetyl-4-(4-but-2-ynyloxy-benzenesulfonyl)-7-dim...)
Affinity DataIC50: 197nMAssay Description:Inhibitory activity against Tumor necrosis factor alpha converting enzymeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50150252(1-Acetyl-4-(4-but-2-ynyloxy-benzenesulfonyl)-7-dim...)
Affinity DataIC50: 682nMAssay Description:In vitro inhibitory activity against matrix metalloprotease-1More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed