BDBM50150084 CHEMBL124700::[2-(2,3-Dihydro-benzo[1,4]dioxin-5-yloxy)-ethyl]-[2-(5-fluoro-1H-indol-3-yl)-ethyl]-amine

SMILES Fc1ccc2[nH]cc(CCNCCOc3cccc4OCCOc34)c2c1

InChI Key InChIKey=VDDABROBOWDPAL-UHFFFAOYSA-N

Data  2 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50150084   

Target5-hydroxytryptamine receptor 1A(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50150084([2-(2,3-Dihydro-benzo[1,4]dioxin-5-yloxy)-ethyl]-[...)
Affinity DataKi:  5.80nMAssay Description:Binding affinity against human 5-hydroxytryptamine 1A receptor in CHO cells labeled with [3H]8-OH-DPAT radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50150084([2-(2,3-Dihydro-benzo[1,4]dioxin-5-yloxy)-ethyl]-[...)
Affinity DataKi:  13.5nMAssay Description:Binding affinity against serotonin transporter in rat cortical tissues using radioligand [3H]paroxetineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50150084([2-(2,3-Dihydro-benzo[1,4]dioxin-5-yloxy)-ethyl]-[...)
Affinity DataIC50: 84.7nMAssay Description:Inhibition concentration against [3H]5-HT uptake by human serotonin transporter in JAR cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed