BDBM50150079 CHEMBL338587::[4-(1H-Indol-3-yl)-butyl]-[2-(1H-indol-4-yloxy)-ethyl]-amine

SMILES C(CCc1c[nH]c2ccccc12)CNCCOc1cccc2[nH]ccc12

InChI Key InChIKey=UIXPCYZWBFDFKV-UHFFFAOYSA-N

Data  2 KI  1 IC50  1 EC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50150079   

TargetSodium-dependent serotonin transporter(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50150079([4-(1H-Indol-3-yl)-butyl]-[2-(1H-indol-4-yloxy)-et...)
Affinity DataIC50: 862nMAssay Description:Inhibition concentration against [3H]5-HT uptake by human serotonin transporter in JAR cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50150079([4-(1H-Indol-3-yl)-butyl]-[2-(1H-indol-4-yloxy)-et...)
Affinity DataEC50:  25.8nMAssay Description:Effective concentration against binding of radioligand [35S]GTP-gamma-S in CHO cells expressing human 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
Target5-hydroxytryptamine receptor 1A(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50150079([4-(1H-Indol-3-yl)-butyl]-[2-(1H-indol-4-yloxy)-et...)
Affinity DataKi:  4.20nMAssay Description:Binding affinity against human 5-hydroxytryptamine 1A receptor in CHO cells labeled with [3H]8-OH-DPAT radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSodium-dependent serotonin transporter(Rat)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50150079([4-(1H-Indol-3-yl)-butyl]-[2-(1H-indol-4-yloxy)-et...)
Affinity DataKi:  19.5nMAssay Description:Binding affinity against serotonin transporter in rat cortical tissues using radioligand [3H]paroxetineMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed