BDBM50149992 CHEMBL3769897

SMILES C1CC1CC(=O)Nc2nnc(s2)N3CCC(CC3)Oc4nnc(s4)NC(=O)CC5CC5

InChI Key InChIKey=JHCGNAVCXZTYNC-UHFFFAOYSA-N

Data  3 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50149992   

TargetGlutaminase kidney isoform, mitochondrial(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50149992(CHEMBL3769897)
Affinity DataIC50: 157nMAssay Description:Inhibition of recombinant HIs-tagged human GAC (residue 72-603 aa) expressed in Escherichia coli after 10 mins using glutamine as substrateMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2017
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutaminase kidney isoform, mitochondrial(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50149992(CHEMBL3769897)
Affinity DataIC50: 157nMAssay Description:Inhibition of recombinant human His-tagged GAC (72 to 603 residues) expressed in Escherichia coli using glutamine as substrate incubated for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetGlutaminase kidney isoform, mitochondrial(Human)
University of Pittsburgh

Curated by ChEMBL
LigandPNGBDBM50149992(CHEMBL3769897)
Affinity DataIC50: 158nMAssay Description:Inhibition of recombinant human His-tagged GAC (72 to 603 residues) expressed in Escherichia coli using glutamine as substrate incubated for 10 minsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/25/2021
Entry Details Article
PubMedPDB3D3D Structure (crystal)