BDBM50149923 CHEMBL3770916

SMILES c1cncc2c1C(=O)NC(=N2)Oc3c[nH]nc3

InChI Key InChIKey=MOMKPBKMLHPDGF-UHFFFAOYSA-N

Data  2 IC50

PDB links: 1 PDB ID matches this monomer.

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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50149923   

TargetLysine-specific demethylase 4C(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50149923(CHEMBL3770916)
Affinity DataIC50: 398nMAssay Description:Inhibition of N-terminal his-tagged human KDM4C expressed in Escherichia coli BL21(DE3) using trimethylated peptide substrate by RFMS assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2017
Entry Details Article
PubMed
TargetLysine-specific demethylase 4C(Human)
Glaxosmithkline

Curated by ChEMBL
LigandPNGBDBM50149923(CHEMBL3770916)
Affinity DataIC50: 7.94E+3nMAssay Description:Inhibition of N-terminal his-tagged full-length human KDM4C transfected in U2OS cells assessed as inhibition of H3K9Me3 demethylation for 24 hrsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
6/24/2017
Entry Details Article
PubMed