BDBM50149658 CHEMBL184930::[3-(3,5-Dichloro-pyridin-2-yl)-2,5-dimethyl-pyrazolo[1,5-a]pyrimidin-7-yl]-dipropyl-amine

SMILES CCCN(CCC)c1cc(C)nc2c(c(C)nn12)-c1ncc(Cl)cc1Cl

InChI Key InChIKey=QBCMIBULNPRCOW-UHFFFAOYSA-N

Data  1 KI  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50149658   

TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50149658([3-(3,5-Dichloro-pyridin-2-yl)-2,5-dimethyl-pyrazo...)
Affinity DataKi:  3.20nMAssay Description:Binding affinity for recombinant human CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Neurocrine Biosciences

Curated by ChEMBL
LigandPNGBDBM50149658([3-(3,5-Dichloro-pyridin-2-yl)-2,5-dimethyl-pyrazo...)
Affinity DataIC50: 49nMAssay Description:Inhibition of CRF-stimulated cAMP production in cells expressing CRF1 receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed