BDBM50149238 4-Hydroxybiphenyl::4-Phenylphenol::4-biphenylol::4-diphenylol::4-hydroxydiphenyl::Biphenyl-4-ol (8)::CHEMBL73380::[1,1'-biphenyl]-4-ol::biphenyl-4-ol::p-biphenylol::p-hydroxybiphenyl::p-hydroxydiphenyl::p-phenylphenol::para-hydroxydiphenyl::para-phenylphenol

SMILES Oc1ccc(cc1)-c1ccccc1

InChI Key InChIKey=YXVFYQXJAXKLAK-UHFFFAOYSA-N

Data  5 KI  2 IC50  3 Kd

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 10 hits for monomerid = 50149238   

TargetStromelysin-1(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149238(p-biphenylol | p-hydroxybiphenyl | p-hydroxydiphen...)
Affinity DataKd:  2.80E+5nMAssay Description:Dissociation constant for Matrix Metalloprotease-3 (MMP-3)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetAndrogen receptor(Rat)
University of Basel

Curated by ChEMBL
LigandPNGBDBM50149238(p-biphenylol | p-hydroxybiphenyl | p-hydroxydiphen...)
Affinity DataIC50: 8.32E+3nMAssay Description:Inhibitory concentration against recombinant rat androgen receptor expressed in Escherichia coli using [3H]methyltrienolone (R 1881)More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
LigandPNGBDBM50149238(p-biphenylol | p-hydroxybiphenyl | p-hydroxydiphen...)
Affinity DataIC50: 1.62E+8nMAssay Description:Inhibitory activity determined against Protein tyrosine phosphatase PTB1BMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/20/2013
Entry Details Article
PubMed
TargetBcl-2-like protein 1(Human)
Taros Chemicals

Curated by ChEMBL
LigandPNGBDBM50149238(p-biphenylol | p-hydroxybiphenyl | p-hydroxydiphen...)
Affinity DataKd:  6.00E+6nMAssay Description:Binding affinity to BCL-XL (unknown origin) by 15N HSQC NMR analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
2/20/2021
Entry Details Article
PubMed
TargetStromelysin-1(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149238(p-biphenylol | p-hydroxybiphenyl | p-hydroxydiphen...)
Affinity DataKd:  2.80E+5nMAssay Description:Binding affinity to human MMP3 catalytic domain (81 to 256 residues) expressed in Escherichia coli BL21 (DE3) pLysS by 15N-HSQC-NMR spectroscopyMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
TargetCarbonic anhydrase 2(Human)
Agri Ibrahim Cecen University

LigandPNGBDBM50149238(p-biphenylol | p-hydroxybiphenyl | p-hydroxydiphen...)
Affinity DataKi:  7.41E+3nMAssay Description:Kinetic studies were performed using the esterase activity method, with 4-nitrophenyl acetate (NPA) as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed
TargetAlbumin(Human)
Molecular Discovery

Curated by ChEMBL
LigandPNGBDBM50149238(p-biphenylol | p-hydroxybiphenyl | p-hydroxydiphen...)
Affinity DataKi:  9.54E+3nMAssay Description:Binding affinity towards human serum albuminMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/23/2020
Entry Details Article
PubMed
TargetCarbonic anhydrase 4(Human)
Agri Ibrahim Cecen University

LigandPNGBDBM50149238(p-biphenylol | p-hydroxybiphenyl | p-hydroxydiphen...)
Affinity DataKi:  1.23E+4nMAssay Description:Kinetic studies were performed using the esterase activity method, with 4-nitrophenyl acetate (NPA) as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 1(Human)
Agri Ibrahim Cecen University

LigandPNGBDBM50149238(p-biphenylol | p-hydroxybiphenyl | p-hydroxydiphen...)
Affinity DataKi:  1.95E+4nMAssay Description:Kinetic studies were performed using the esterase activity method, with 4-nitrophenyl acetate (NPA) as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed
TargetCarbonic anhydrase 6(Human)
Agri Ibrahim Cecen University

LigandPNGBDBM50149238(p-biphenylol | p-hydroxybiphenyl | p-hydroxydiphen...)
Affinity DataKi:  8.50E+4nMAssay Description:Kinetic studies were performed using the esterase activity method, with 4-nitrophenyl acetate (NPA) as substrate.More data for this Ligand-Target Pair
In Depth
Date in BDB:
7/17/2017
Entry Details Article
PubMed