BDBM50149225 3,4-Dihydroxy-benzaldehyde O-methyl-oxime::CHEMBL117488

SMILES CO\N=C\c1ccc(O)c(O)c1

InChI Key InChIKey=QKIMWRSLZXAMIW-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50149225   

TargetProto-oncogene tyrosine-protein kinase Src(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149225(3,4-Dihydroxy-benzaldehyde O-methyl-oxime | CHEMBL...)
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibition of c-Src tyrosine kinaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/30/2012
Entry Details Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Sunesis Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50149225(3,4-Dihydroxy-benzaldehyde O-methyl-oxime | CHEMBL...)
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibition of c-Src (unknown origin) using biotin-KVEKIGEGTYGVVYK as substrate by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/21/2022
Entry Details Article
PubMed
Target1-deoxy-D-xylulose 5-phosphate reductoisomerase(Escherichia coli (strain K12))
The Johns Hopkins University School of Medicine

LigandPNGBDBM50149225(3,4-Dihydroxy-benzaldehyde O-methyl-oxime | CHEMBL...)
Affinity DataKi: >2.00E+5nMpH: 8.0Assay Description:DXP synthase reaction mixtures containing HEPES (100 mM, pH 8.0), MgCl2 (2 mM), NaCl (5 mM), ThDP (1 mM), BSA (1 mg/mL), pyruvate (12.5-250 µM), D-GA...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2015
Entry Details Article
PubMed