BDBM50149101 3-[2-(5-Bromo-thiophen-2-yl)-1H-benzoimidazol-5-yl]-N-(3,4,5,6-tetrahydro-2H-[1,4']bipyridinyl-4-ylmethyl)-propionamide::CHEMBL125491

SMILES Brc1ccc(s1)-c1nc2ccc(CCC(=O)NCC3CCN(CC3)c3ccncc3)cc2[nH]1

InChI Key InChIKey=XGOHRXQNQVENKV-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50149101   

TargetSerine protease 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50149101(3-[2-(5-Bromo-thiophen-2-yl)-1H-benzoimidazol-5-yl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity of the compoumd against human trypsin was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50149101(3-[2-(5-Bromo-thiophen-2-yl)-1H-benzoimidazol-5-yl...)
Affinity DataIC50: 58nMAssay Description:Binding affinity of the compoumd to human coagulation factor XaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50149101(3-[2-(5-Bromo-thiophen-2-yl)-1H-benzoimidazol-5-yl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity against human thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed