BDBM50149098 CHEMBL125552::N-[3-Chloro-4-(3-oxo-morpholin-4-yl)-phenyl]-3-[2-(5-chloro-thiophen-2-yl)-1H-benzoimidazol-5-yl]-propionamide

SMILES Clc1ccc(s1)-c1nc2ccc(CCC(=O)Nc3ccc(N4CCOCC4=O)c(Cl)c3)cc2[nH]1

InChI Key InChIKey=JKCWZKGFHCEGDT-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50149098   

TargetProthrombin(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50149098(N-[3-Chloro-4-(3-oxo-morpholin-4-yl)-phenyl]-3-[2-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity against human thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50149098(N-[3-Chloro-4-(3-oxo-morpholin-4-yl)-phenyl]-3-[2-...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity of the compoumd against human trypsin was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCoagulation factor X(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50149098(N-[3-Chloro-4-(3-oxo-morpholin-4-yl)-phenyl]-3-[2-...)
Affinity DataIC50: 7nMAssay Description:Binding affinity of the compoumd to human coagulation factor XaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed