BDBM50149077 6-[2-(5-Bromo-thiophen-2-yl)-1H-benzoimidazol-5-yl]-4-methyl-4,5-dihydro-2H-pyridazin-3-one::CHEMBL124427

SMILES CC1CC(=NNC1=O)c1ccc2nc([nH]c2c1)-c1ccc(Br)s1

InChI Key InChIKey=ZUHSHMSFEYULCI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50149077   

TargetCoagulation factor X(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50149077(6-[2-(5-Bromo-thiophen-2-yl)-1H-benzoimidazol-5-yl...)
Affinity DataIC50: 980nMAssay Description:Binding affinity of the compoumd to human coagulation factor XaMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetProthrombin(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50149077(6-[2-(5-Bromo-thiophen-2-yl)-1H-benzoimidazol-5-yl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity against human thrombin.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSerine protease 1(Human)
Merck

Curated by ChEMBL
LigandPNGBDBM50149077(6-[2-(5-Bromo-thiophen-2-yl)-1H-benzoimidazol-5-yl...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity of the compoumd against human trypsin was determinedMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed