BDBM50149039 Biphenyl-4-carboxylic acid 1-(3-phenyl-propyl)-piperidin-3-ylmethyl ester::CHEMBL122218

SMILES O=C(OCC1CCCN(CCCc2ccccc2)C1)c1ccc(cc1)-c1ccccc1

InChI Key InChIKey=GQIUISIPQMWLHH-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50149039   

LigandPNGBDBM50149039(Biphenyl-4-carboxylic acid 1-(3-phenyl-propyl)-pip...)
Affinity DataIC50: 3.00E+3nMAssay Description:Effect on alpha3-beta4 neuronal nicotinic acetylcholine receptor-stimulated adrenal catecholamine secretionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
The Ohio State University

Curated by ChEMBL
LigandPNGBDBM50149039(Biphenyl-4-carboxylic acid 1-(3-phenyl-propyl)-pip...)
Affinity DataIC50: 6.31E+3nMAssay Description:Antagonist activity at human nAChR alpha4/beta2 receptor expressed in HEK ts201 cells assessed as calcium accumulation by fluorescence analysisMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/22/2013
Entry Details Article
PubMed