BDBM50148867 CHEMBL3770783::US10533010, Example I-1::US11208415, Example I-1

SMILES Cc1cc(OCCCc2c([nH]c3ccccc23)C(=O)NC(C)(C)C)cc(C)c1Cl

InChI Key InChIKey=ULBIMQZBSJJTLE-UHFFFAOYSA-N

Data  3 KI

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50148867   

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50148867(CHEMBL3770783 | US10533010, Example I-1 | US112084...)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of recombinant Mcl-1 (residues 172-327) (unknown origin) using FITC-AHx-EARIAQELRRIGDEFNETYTR-NH2 as substrate after 90 mins by fluorescen...More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/22/2017
Entry Details Article
PubMed
TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50148867(CHEMBL3770783 | US10533010, Example I-1 | US112084...)
Affinity DataKi:  5.50E+3nMAssay Description:Compound affinity was measured using a fluorescence polarization anisotropy competition assay. Anisotropy measurements were carried out in 384-well, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/2/2020
Entry Details
Go to US Patent

TargetInduced myeloid leukemia cell differentiation protein Mcl-1(Human)
Therachem Research Medilab (India)

Curated by ChEMBL
LigandPNGBDBM50148867(CHEMBL3770783 | US10533010, Example I-1 | US112084...)
Affinity DataKi:  5.50E+3nMAssay Description:Compound affinity was measured using a fluorescence polarization anisotropy competition assay. Anisotropy measurements were carried out in 384-well, ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/3/2022
Entry Details
Go to US Patent