BDBM50148762 CHEMBL3142917::[1-[2',5'-Bis-O-(tert-butyldimethylsilyl)-beta-D-ribofuranosyl]-3-N-[3-[[[(methoxycarbonyl)hydroxyphosphonyl]oxy]-propyl]thymine]-3''-spiro-5''-(4''-amino-1'',2''-oxathiole-2'',2''-dioxide); Sodium ion

SMILES COC(=O)P([O-])(=O)OCCCn1c(=O)c(C)cn([C@@H]2O[C@H](CO[Si](C)(C)C(C)(C)C)[C@@]3(OS(=O)(=O)C=C3N)[C@H]2O[Si](C)(C)C(C)(C)C)c1=O

InChI Key InChIKey=VAWQHGBUNNNRMH-UHFFFAOYSA-M

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50148762   

TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50148762([1-[2',5'-Bis-O-(tert-butyldimethylsilyl)-beta-D-r...)
Affinity DataIC50: 3.94E+5nMAssay Description:Inhibitory concentration against wild type HIV-1/138Lys reverse transcriptase (RT) using [3H]dGTP as a radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
Instituto De QuíMica MéDica (Csic)

Curated by ChEMBL
LigandPNGBDBM50148762([1-[2',5'-Bis-O-(tert-butyldimethylsilyl)-beta-D-r...)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibitory concentration against wild type HIV-1 reverse transcriptase (RT) using poly rC.dG as the template or primerMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed