BDBM50148716 CHEMBL334158::[5-(3-Amino-3-methyl-but-1-ynyl)-2-chloro-phenyl]-[4-(2,4-difluoro-phenylamino)-phenyl]-methanone

SMILES CC(C)(N)C#Cc1ccc(Cl)c(c1)C(=O)c1ccc(Nc2ccc(F)cc2F)cc1

InChI Key InChIKey=PUEUSKZGFHEWJE-UHFFFAOYSA-N

Data  1 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 1 hit for monomerid = 50148716   

TargetMitogen-activated protein kinase 14(Mouse)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50148716([5-(3-Amino-3-methyl-but-1-ynyl)-2-chloro-phenyl]-...)
Affinity DataIC50: 6.00E+3nMAssay Description:Inhibition of murine His-Mitogen-activated protein kinase p38 alpha phosphorylation.More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed