BDBM50148671 4-(2-(5-fluoropyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl)quinoline::4-[2-(5-Fluoro-pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazol-3-yl]-quinoline::CHEMBL325405

SMILES Fc1ccc(nc1)-c1nn2CCCc2c1-c1ccnc2ccccc12

InChI Key InChIKey=IKJMJDPMGHFSNH-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50148671   

TargetMitogen-activated protein kinase 14(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50148671(4-[2-(5-Fluoro-pyridin-2-yl)-5,6-dihydro-4H-pyrrol...)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibitory activity against Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThyroid hormone receptor beta(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50148671(4-[2-(5-Fluoro-pyridin-2-yl)-5,6-dihydro-4H-pyrrol...)
Affinity DataIC50: 151nMAssay Description:Inhibitory activity against TGF-beta type I receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50148671(4-[2-(5-Fluoro-pyridin-2-yl)-5,6-dihydro-4H-pyrrol...)
Affinity DataIC50: 151nMAssay Description:Inhibition of TGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed