BDBM50148667 3-(4-Fluoro-phenyl)-2-(6-trifluoromethyl-pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole::3-(4-fluorophenyl)-2-(6-(trifluoromethyl)pyridin-2-yl)-5,6-dihydro-4H-pyrrolo[1,2-b]pyrazole::CHEMBL333798

SMILES Fc1ccc(cc1)-c1c2CCCn2nc1-c1cccc(n1)C(F)(F)F

InChI Key InChIKey=JFQHZKYTJUOQDK-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50148667   

TargetMitogen-activated protein kinase 14(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50148667(3-(4-Fluoro-phenyl)-2-(6-trifluoromethyl-pyridin-2...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibitory activity against Mitogen-activated protein kinase p38More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetThyroid hormone receptor beta(Human)
Eli Lilly

Curated by ChEMBL
LigandPNGBDBM50148667(3-(4-Fluoro-phenyl)-2-(6-trifluoromethyl-pyridin-2...)
Affinity DataIC50: 877nMAssay Description:Inhibitory activity against TGF-beta type I receptorMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTGF-beta receptor type-1(Human)
Sichuan University

Curated by ChEMBL
LigandPNGBDBM50148667(3-(4-Fluoro-phenyl)-2-(6-trifluoromethyl-pyridin-2...)
Affinity DataIC50: 877nMAssay Description:Inhibition of TGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2010
Entry Details Article
PubMed