BDBM50148578 CHEMBL3770730

SMILES NC(C(=O)Nc1ccc2cnccc2c1)c1ccccc1

InChI Key InChIKey=FCVSCBFMVWNZGA-UHFFFAOYSA-N

Data  1 KI  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50148578   

TargetRho-associated protein kinase 1(Human)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50148578(CHEMBL3770730)
Affinity DataIC50: 6nMAssay Description:Inhibition of ROCK1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2017
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50148578(CHEMBL3770730)
Affinity DataIC50: 1.5nMAssay Description:Inhibition of ROCK2 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
6/21/2017
Entry Details Article
PubMed
TargetRho-associated protein kinase 2(Human)
Georgia Institute of Technology

Curated by ChEMBL
LigandPNGBDBM50148578(CHEMBL3770730)
Affinity DataKi:  1.5nMAssay Description:Inhibition of ROCK2 (unknown origin) using RSK2 peptide (KKRNRTLTK) as substrate after 180 mins by luminescent kinase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/14/2017
Entry Details Article
PubMed