BDBM50148418 CHEMBL119256::[3-(4-Octyl-benzylamino)-propyl]-phosphonic acid

SMILES CCCCCCCCc1ccc(CNCCCP(O)(O)=O)cc1

InChI Key InChIKey=HXDPHSXYLHIVSE-UHFFFAOYSA-N

Data  7 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 7 hits for monomerid = 50148418   

TargetSphingosine 1-phosphate receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50148418([3-(4-Octyl-benzylamino)-propyl]-phosphonic acid |...)
Affinity DataIC50: 0.600nMAssay Description:Binding affinity to human sphingosine 1-phosphate receptor 1 expressed in CHO cells was determined by using [33P]-S1P as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetLysophosphatidic acid receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50148418([3-(4-Octyl-benzylamino)-propyl]-phosphonic acid |...)
Affinity DataIC50: 26nMAssay Description:Binding affinity to human sphingosine 1-phosphate receptor 4 expressed in CHO cells was determined by using [33P]-S1P as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50148418([3-(4-Octyl-benzylamino)-propyl]-phosphonic acid |...)
Affinity DataIC50: 21nMAssay Description:Binding affinity towards human sphingosine 1-phosphate receptor 3 expressed in CHO cells was determined by using [33P]-S1P as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50148418([3-(4-Octyl-benzylamino)-propyl]-phosphonic acid |...)
Affinity DataIC50: 1.00E+4nMAssay Description:Binding affinity towards human sphingosine 1-phosphate receptor 2 expressed in CHO cells was determined by using [33P]-S1P as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 2(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50148418([3-(4-Octyl-benzylamino)-propyl]-phosphonic acid |...)
Affinity DataIC50: 5.5nMAssay Description:Binding affinity to human sphingosine 1-phosphate receptor 5 expressed in CHO cells was determined by using [33P]-S1P as radioligandMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 1(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50148418([3-(4-Octyl-benzylamino)-propyl]-phosphonic acid |...)
Affinity DataIC50: 0.200nMAssay Description:Displacement of [33P]-S1P from human S1P1 receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2019
Entry Details Article
PubMed
TargetSphingosine 1-phosphate receptor 3(Human)
Merck Research Laboratories

Curated by ChEMBL
LigandPNGBDBM50148418([3-(4-Octyl-benzylamino)-propyl]-phosphonic acid |...)
Affinity DataIC50: 2.70nMAssay Description:Displacement of [33P]-S1P from human S1P3 receptor expressed in CHO cell membranesMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/13/2019
Entry Details Article
PubMed