BDBM50148228 1-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-cyclobutanecarboxylic acid hydroxyamide::CHEMBL115283

SMILES ONC(=O)C1(CCC1)NS(=O)(=O)c1ccc(Oc2ccc(F)cc2)cc1

InChI Key InChIKey=SHSBTGZNXOPCNV-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50148228   

TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50148228(1-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-cycl...)
Affinity DataIC50: 280nMAssay Description:Inhibitory activity against human matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50148228(1-[4-(4-Fluoro-phenoxy)-benzenesulfonylamino]-cycl...)
Affinity DataIC50: 0.530nMAssay Description:Inhibitory activity against matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed