BDBM50148215 4-[4-(4-Fluoro-pyridin-2-yloxy)-benzenesulfonylamino]-tetrahydro-pyran-4-carboxylic acid hydroxyamide::CHEMBL113705

SMILES ONC(=O)C1(CCOCC1)NS(=O)(=O)c1ccc(Oc2cc(F)ccn2)cc1

InChI Key InChIKey=AWPPALPLPMDYKF-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50148215   

TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50148215(4-[4-(4-Fluoro-pyridin-2-yloxy)-benzenesulfonylami...)
Affinity DataIC50: 14nMAssay Description:Inhibitory activity against matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50148215(4-[4-(4-Fluoro-pyridin-2-yloxy)-benzenesulfonylami...)
Affinity DataIC50: 3.80E+3nMAssay Description:Inhibitory activity against human matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed