BDBM50148212 4-[4-(4-Methoxy-phenoxy)-benzenesulfonylamino]-tetrahydro-pyran-4-carboxylic acid hydroxyamide::CHEMBL114906

SMILES COc1ccc(Oc2ccc(cc2)S(=O)(=O)NC2(CCOCC2)C(=O)NO)cc1

InChI Key InChIKey=CIECVEXIXKIUIZ-UHFFFAOYSA-N

Data  2 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
Find this compound or compounds like it in BindingDB:
   Substructure
Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 2 hits for monomerid = 50148212   

TargetCollagenase 3(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50148212(4-[4-(4-Methoxy-phenoxy)-benzenesulfonylamino]-tet...)
Affinity DataIC50: 0.870nMAssay Description:Inhibitory activity against matrix metalloprotease-13 (MMP-13)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed
TargetInterstitial collagenase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50148212(4-[4-(4-Methoxy-phenoxy)-benzenesulfonylamino]-tet...)
Affinity DataIC50: 780nMAssay Description:Inhibitory activity against human matrix metalloprotease-1 (MMP-1)More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/10/2012
Entry Details Article
PubMed