BDBM50148173 CHEMBL326854::N-Benzyl-2-[2-(4-methyl-piperazin-1-yl)-3-phenyl-3,4-dihydro-quinazolin-4-yl]-acetamide::N-benzyl-2-(2-(4-methylpiperazin-1-yl)-3-phenyl-3,4-dihydroquinazolin-4-yl)acetamide

SMILES CN1CCN(CC1)C1=Nc2ccccc2C(CC(=O)NCc2ccccc2)N1c1ccccc1

InChI Key InChIKey=MVQDDDPVGORFBZ-UHFFFAOYSA-N

Data  4 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 4 hits for monomerid = 50148173   

TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50148173(N-Benzyl-2-[2-(4-methyl-piperazin-1-yl)-3-phenyl-3...)
Affinity DataIC50: 3.58E+4nMAssay Description:Inhibition of human T-type calcium channel alpha1G in HEK293 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2013
Entry Details Article
PubMed
TargetVoltage-dependent T-type calcium channel subunit alpha-1G(Human)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50148173(N-Benzyl-2-[2-(4-methyl-piperazin-1-yl)-3-phenyl-3...)
Affinity DataIC50: 3.58E+4nMAssay Description:Concentration of the compounds required for inhibition of HEK293 cells (alpha1G T-type)More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCholinesterase(Horse)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50148173(N-Benzyl-2-[2-(4-methyl-piperazin-1-yl)-3-phenyl-3...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of equine serum BCHE using butyrylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured for 5 m...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2019
Entry Details Article
PubMed
TargetAcetylcholinesterase(Electric eel)
Kyung Hee University

Curated by ChEMBL
LigandPNGBDBM50148173(N-Benzyl-2-[2-(4-methyl-piperazin-1-yl)-3-phenyl-3...)
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of electric eel AChE using acetylthiocholine iodide as substrate preincubated for 20 mins followed by substrate addition measured for 5 mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/21/2019
Entry Details Article
PubMed