BDBM50148163 CHEMBL112747::[4-(4-Methoxy-pyridin-2-ylamino)-piperidin-1-yl]-phenyl-methanone

SMILES COc1ccnc(NC2CCN(CC2)C(=O)c2ccccc2)c1

InChI Key InChIKey=ULYAVZFGXSQWBB-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Similarity at least:  must be >=0.5
Exact match

Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50148163   

TargetNitric oxide synthase, endothelial(Human)
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50148163([4-(4-Methoxy-pyridin-2-ylamino)-piperidin-1-yl]-p...)
Affinity DataIC50: 1.00E+5nMAssay Description:In vitro inhibition of human endothelial nitric oxide synthase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, inducible(Human)
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50148163([4-(4-Methoxy-pyridin-2-ylamino)-piperidin-1-yl]-p...)
Affinity DataIC50: 530nMAssay Description:In vitro inhibition of human Inducible nitric oxide synthase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetNitric oxide synthase, brain(Human)
Astrazeneca R&D Charnwood

Curated by ChEMBL
LigandPNGBDBM50148163([4-(4-Methoxy-pyridin-2-ylamino)-piperidin-1-yl]-p...)
Affinity DataIC50: 2.80E+4nMAssay Description:In vitro inhibition of human neuronal nitric oxide synthase.More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed