BDBM50148053 (1E)-1-(1,1'-biphenyl-3-yl)ethan-1-one thiosemicarbazone::CHEMBL108035

SMILES CC(=NNC(N)=S)c1cccc(c1)-c1ccccc1

InChI Key InChIKey=OEMPMQMUBMCYOI-UHFFFAOYSA-N

Data  3 IC50

  Tab Delimited (TSV)   2D SDfile   Computed 3D by Vconf -m prep SDfile
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Activity Spreadsheet -- Enzyme Inhibition Constant Data from BindingDB

Found 3 hits for monomerid = 50148053   

TargetCysteine protease(Trypanosoma brucei rhodesiense)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50148053((1E)-1-(1,1'-biphenyl-3-yl)ethan-1-one thiosemicar...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of rhodesain from Trypanosoma brucei rhodesienseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCruzipain(Trypanosoma cruzi)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50148053((1E)-1-(1,1'-biphenyl-3-yl)ethan-1-one thiosemicar...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of cruzain from Trypanosoma cruziMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetCruzipain(Trypanosoma cruzi)
University of California San Francisco

Curated by ChEMBL
LigandPNGBDBM50148053((1E)-1-(1,1'-biphenyl-3-yl)ethan-1-one thiosemicar...)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of recombinant Trypanosoma cruzi Cruzipain using Z-Phe-Arg-AMC as substrate preincubated for 5 mins followed by substrate addition by spec...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/14/2024
Entry Details
PubMed